Histidine is an essential amino acid, manufactured in sufficient quantities in adults, but children may at some time have a shortage of this important vitamin. It is one of the basic (reference to pH factor) amino acids due to its aromatic nitrogen-heterocyclic imidazole side chain. This amino acid is metabolized into the neurotransmitter histamine and the set of genes that produce the enzymes responsible for histidine synthesis.


What it is

Histamine is an important immune system chemical. The availability of Histidine influcences the production of histamine. Histidine taken with B3 and B6 is what transfroms Histidine to histamine.


What it does

Histidine is found abundantly in hemoglobin. It has been used in the treatment of rheumatoid arthritis, allergies, ulcers and anemia. It is essential for the growth and repair of tissues; important for the maintenance of the myelin sheaths, which protect nerve cells.

It is needed for the production of both red and white blood cells. Histidine protects the body from radiation damage; lowers blood pressure. It aids in the removal of heavy metals from the body; aids in sexual arousal.



  • Helps maintain myelin sheaths, which protect nerve cells
  • Needed for producing red and white blood cells
  • Protects body from radiation damage
  • Important to the growth and repair of tissues
  • Supplemental histidine with B3 and B6 may help improve sexual functioning and pleasure
  • Aids in removing heavy metals from the system
  • Helps lower blood pressure
  • Histamine aids in sexual arousal



The daily dosage requirement is recommended as 8-10 mg per day per kilogram of body weight.