Glycine is one of the non-essential amino acids and is used to help create muscle tissue and convert glucose into energy. It is also essential to maintaining healthy central nervous and digestive systems, and has recently been shown to provide protection via antioxidants from some types of cancer.


What it is

Glycine is considered a glucogenic amino acid, which means it helps supply the body with glucose needed for energy. It helps regulate blood sugar levels, and thus glycine supplementation may be useful for treating symptoms characterized by low energy and fatigue, such as hypoglycemia, anemia, and Chronic Fatigue Syndrome (CFS).


What it does

Glycine is used in the body to help construct normal DNA and RNA strands-the genetic material needed for proper cellular function and formation. It helps prevent the breakdown of muscle by boosting the body's levels of creatine, a compound that helps build muscle mass. High concentrations of glycine are found not only in the muscles, but in the skin and other connective tissues as well. Almost 1/3 of collagen, which keeps the skin and connective tissue firm and flexible, is composed of glycine. (High amounts of Glycine are also found in gelatin, which is a form of denatured collagen). Without glycine the body would not be able to repair damaged tissues; the skin would become slack as it succumbed to UV rays, oxidation, and free radical damage, and wounds would never heal.

Glycine is essential for a healthy, normally functioning digestive system. It helps regulate the synthesis of the bile acid used to digest fats, and is included in many commercial gastric antacid agents.



  • Retards muscle degeneration
  • Improve glycogen storage, thus freeing up glucose for energy needs
  • Promotes a healthy prostate
  • Promotes the proper function of the central nervous system and immune system
  • Useful for repairing damaged tissue and promotes healing



Doses used for management of schizophrenia have ranged from 40 to 90 grams daily. Studies examining the role of glycine in the treatment of benign prostatic hyperplasia used doses ranging from 390 milligrams to 780 milligrams per day. Supplemental use of glycine at levels of 1 to 3 grams per day is useful in the treatment of certain forms of bipolar depression (manic depression).